Can Glutathione Reduce Dark Spots and Pigmentation?

The most common skin concerns in the Indian scenario include dark spots, uneven skin tone as well as pigmentation. There are actually so many factors that can cause the normal skin tone to appear darker and uneven.

These may include post-inflammatory hyperpigmentation, exposure to harmful UV rays, post-acne marks or may be hormonal fluctuations. Glutathione has gained quite a lot of attention and popularity because of its action towards improving the skin tone and enhancing the skin health.

It is basically a natural antioxidant that is produced by the body and it’s also available for consumption in the oral supplementation and topical glutathione dark spot removal skincare regimens for dark spots and pigmentation. 

The real question arises here is, if glutathione is actually able to reduce the blemishes from the skin or is it just a marketing gimmick. 

Read on more to explore and deeply understand the scientific explanation behind the action of glutathione.

What Is Glutathione?

This master antioxidant is basically a tripeptide molecule that is made from three amino acids including

• Cysteine - A semi-essential amino acid that is produced naturally by the body but also requires oral consumption to meet the requirements of the body. It mainly assists in improving the overall skin health.
• Glycine - This is a non-essential amino acid that is mainly helpful to promote the skin health and it additionally supports the metabolic processes inside the body. 
• Glutamic Acid - It is also a non-essential amino acid that is generally produced by the body itself. It is helpful in providing the skin with moisturization.

The table below gives you a quick glance at the building blocks of Glutathione that are mainly responsible for its effectiveness:

Building Blocks Of Glutathione

Glutathione or γ-L-glutamyl-L-cysteinylglycine is an interesting tripeptide that plays important roles in maintaining the skin tone and the overall barrier health. 

Melanin is actually the main pigment that generally influences the overall skin tone. Its production and distribution contribute to the visibility of the dark spots as well as hyperpigmentation on the skin. 

Many skincare specialists have investigated and researched on the beneficial properties of the glutathione. Let’s understand the scientific explanation behind the action of Glutathione for dark spots and pigmentation reduction but before that you need to take a quick look at how a dark spot formation/pigmentation may usually take place.

How Dark Spots & Pigmentation Forms 

How Glutathione Works?

Melanin is basically produced by the cells called melanocytes with the help of enzyme tyrosinase. Glutathione affects the melanin synthesis process by influencing the tyrosinase activity and additionally provides the relief from oxidative stress on the skin 

As per a recent clinical trial study on humans, the dark spots reduction was observed among the Asian women within 6 to 12 weeks.

The possible mechanisms of action to reduce the dark spots & pigmentation include

Anti-Oxidant Effect

The glutathione possesses anti-oxidant action that scavenges the damaging free radicals on the skin surface with the thiol moiety of the cysteine within glutathione that helps prevent the oxidative distress on the skin due to prolonged exposure to the solar radiations, environmental pollution, etc. It additionally provides a calming effect to the skin barrier.

Moisturization Effect

The glutamyl moiety of the glutathione aids in supporting the natural moisturization factor which keeps the moisture barrier intact and prevents the rapid TEWL (Transepidermal Water Loss) as well as dehydration. It helps in enhancing the smooth, healthy as well as radiant skin barrier by its humectant properties that helps to draw in the water molecules and bind them to the skin barrier to keep it hydrated as well as moisturized.

Collagen Booster

The Collagen is a vital dermal fiber that supports the overall structural integrity of the skin barrier. Glutathione basically promotes collagen production and also prevents its degradation due to oxidative stress as well as the activation of matrix metalloproteinases (enzymes that damage collagen).

Metabolic Support

The oral intake of glutathione aids with the various metabolic processes inside the body. Majorly synthesized in the liver, the glutathione is important for hepatic action on insulin sensitization agents that is vital for the regulation as well as utilisation of lipid, glucose and amino acids. A better gut health supports better overall skin health too. 

How You Can Add Glutathione To Your Daily Routine?

You can simply intake glutathione for hyperpigmentation in the formulation of tablets on a daily basis to help with the skin rejuvenation. 

Glutiford presents the top recommended Glutathione based tablets for you that can actually help you to improve your skin barrier health with utmost ease. 

1. Glutiford Effervescent Tablets

These tablets are very easy for oral consumption of glutathione pigmentation & dark spot reduction on a daily basis. What you need to do is:

• Take a single tablet at a time
• Drop it in a glass of water
• Let it dissolve
• Drink immediately

The effervescent tablet formula absorbs rapidly inside the body and allows faster absorption. It incorporates the liposomally encapsulated form of glutathione to help with the maximal absorption and high effectiveness. 

The table below describes the key active ingredients that actually help you to rejuvenate your skin and aid in reducing the pigmentation:

2. Glutiford Tablets

These tablets are ready to use for oral intake directly with water. They also are designed with the Liposomal Technology to aid in reducing the hyperpigmentation marks as well as uneven skin tone. The tablets is composed with the following actives that are very helpful in supporting the skin radiance:

• 600 mg Liposomal Glutathione

Provides the skin with anti-oxidant and moisturization support with boosting the collagen to support the barrier health.

• 100 mg Alpha-Lipoic Acid

Helps protect cells from oxidative stress due to longer periods of exposure under the solar radiations, pollution, heat, high humidity, etc.

• 105 mg Grape Seed Extract

This extract enhances the anti-oxidant action of glutathione in a synergistic way to promote overall skin health as well as a radiant glow. 

• 50 mg Licorice extract

Acts on the existing dark spots to help disperse the accumulated melanin and also prevent the tyrosinase enzyme that is responsible for the melanin and dark spots formation.

• Vitamin B3, E & C

These vitamins help improve the cellular health of the skin barrier as well as nourish the skin with the vital nutrients to support the skin rejuvenation.

Summary

Dark spots and pigmentation on the skin can be due to sun exposure, acne marks, hormonal changes and post-inflammatory hyperpigmentation. Glutathione is a very helpful antioxidant that aids in minimizing the dark spots and pigmentation. Being a tripeptide molecule, glutathione helps in supporting anti-oxidant action, moisturization, collagen boosting as well as metabolic processes.

You can simply intake Glutathione in the formulation of tablets on a daily basis to help with the skin rejuvenation. Glutiford offers the top recommended OTC tablets for Glutathione including

• Glutiford Effervescent Tablets with the goodness of Liposomal Glutathione (600 mg), Vit. C & Hyaluronic Acid
• Glutiford Tablets enriched with the powers of Liposomal Glutathione (600 mg), Licorice, Alpha Lipoic Acid & Vitamin B3, E & C.

Take 1 tablet a day for better results. Consult a doctor if you get any side effects or feel any kind of discomfort, bowel irritation, nausea or vomiting. 

FAQs - Frequently Asked Questions

Ques. What is Glutathione?

Ans. Glutathione is a master antioxidant is basically a tripeptide molecule that is made from three amino acids including cysteine, glutamic acid as well as glycine. 

Ques. How does Glutathione work to enhance the radiant glow of my skin?

Ans. Glutathione basically provides the anti-oxidant support to the skin that prevents the oxidative stress on the skin to stimulate the darker melanin (Eumelanin) production as well as shifts it to the lighter melanin (Pheomelanin) synthesis improving the overall even skin tone and the radiant glow of the skin.

Ques. How many tablets of Glutathione should I take in a day?

Ans. You can take 1 tablet a day or you may use it as prescribed by your doctor or registered medical practitioner. 

Ques. Which is the best Glutathione tablet in the market?

Ans. Glutiford Effervescent Tablets are the best in the market as they have the following benefits:

• Easy and quick for oral consumption
• Affordable
• Provide 600mg liposomal glutathione
• Additional support of Vit. C, hyaluronic acid
• Anti-oxidant support of grapeseed as well as blueberry extracts

Ques. How does Glutathione provide anti-oxidant support?

Ans. Glutathione helps in scavenging the damaging free radicals on the skin surface with the thiol moiety of the cysteine within glutathione that helps prevent the oxidative distress on the skin due to prolonged exposure to the solar radiations, environmental pollution, high heat, humidity, etc. It additionally provides a calming effect to the skin barrier.

Ques. What are the benefits of taking 1 tablet of Glutathione everyday?

Ans.  The benefits of taking Glutathione tablet once a day are as follows:

• Reduction in dark spots & pigmentation
• More even-toned skin
• Additional barrier support with collagen boost
• Moisturization of the skin
• Improvement in overall barrier health
• Rejuvenation of damaged skin barrier